What Is Lenisna (PDLLA) and How Does It Work?
Lenisna is an innovative hybrid filler that combines the benefits of poly-D,L-lactic acid (PDLLA) and non-crosslinked hyaluronic acid (HA) to provide both immediate and long-lasting skin rejuvenation. This advanced injectable treatment is designed to restore volume, improve skin elasticity, and stimulate collagen production, making it a popular choice for those seeking natural, gradual anti-ageing results. For those interested in professional care, aesthetic clinic INNODERM in London offers Lenisna treatments alongside a full range of cosmetology services tailored to your beauty needs.
What Is Lenisna?
Lenisna is a unique combination filler that leverages the instant volumizing effect of hyaluronic acid with the powerful collagen-stimulating properties of PDLLA. PDLLA is a biocompatible and biodegradable polymer that has been used in aesthetic medicine since 2009 for its ability to promote collagen and elastin synthesis. The hyaluronic acid component provides immediate hydration and plumping, while PDLLA microparticles gradually encourage the skin to regenerate from within.
This dual-action mechanism makes Lenisna particularly effective for treating deep wrinkles, skin laxity, and volume loss in areas such as the face, neck, and décolletage. The treatment not only fills and smooths but also improves skin texture and firmness over time.
How Does Lenisna Work?
Lenisna works through a two-step process:
Immediate Volume Restoration: The non-crosslinked hyaluronic acid in Lenisna instantly adds volume to hollow or sagging areas, softening wrinkles and enhancing facial contours right after injection.
Long-Term Collagen Stimulation: The PDLLA microparticles activate fibroblasts, the skin cells responsible for collagen production. This stimulation leads to new collagen and elastin formation over several months, resulting in firmer, tighter, and more youthful skin.
This combination allows Lenisna to deliver fast visible improvements alongside gradual, natural rejuvenation that can last up to two years or more. Unlike traditional fillers that only add volume temporarily, Lenisna improves the skin's underlying structure, providing sustained anti-ageing benefits.

Lenisna Before and After: What to Expect
Lenisna before and after photos typically show a noticeable enhancement in facial volume and skin quality. Patients often experience:
Smoother skin with reduced deep wrinkles and folds
Improved skin elasticity and firmness
Restored youthful contours, especially in the cheeks, jawline, and temples
Brighter, more hydrated skin with a natural glow
The initial plumping effect from hyaluronic acid is visible immediately, while the full benefits of collagen stimulation develop gradually over 2 to 3 months. Results are long-lasting, and maintenance treatments can extend the rejuvenating effects even further.
Treatment Process and Safety
Lenisna injections are performed by trained medical professionals in a clinical setting. The product is injected into the deep dermis or subdermal layers, depending on the treatment area and desired outcome. A typical treatment course involves two to three sessions spaced about 4 to 6 weeks apart to optimize collagen production and volumization.
One of the advantages of Lenisna is that its unique round-shaped PDLLA molecules combined with non-crosslinked hyaluronic acid eliminate the need for post-treatment massage, making the experience more comfortable for patients.
Side effects are generally mild and temporary, including slight swelling, redness, or bruising at the injection sites. Lenisna has received regulatory approvals in various countries, confirming its safety and efficacy.
Why Choose Lenisna at Aesthetic Clinic INNODERM in London?

Aesthetic clinic INNODERM in London offers Lenisna as part of its comprehensive cosmetology services, providing expert consultations and personalized treatment plans. The clinic’s experienced practitioners ensure precise administration of Lenisna to achieve natural-looking, long-lasting results tailored to individual skin concerns.
INNODERM combines traditional aesthetic expertise with cutting-edge technology, making it an ideal destination for those seeking advanced injectable treatments like Lenisna for facial rejuvenation.
Conclusion
Lenisna (PDLLA) is a cutting-edge hybrid filler that offers the best of both worlds: immediate volume enhancement from hyaluronic acid and long-term collagen stimulation from PDLLA. This innovative treatment addresses deep wrinkles, skin laxity, and volume loss while improving overall skin quality and elasticity. Lenisna before and after results demonstrate its ability to deliver natural, youthful rejuvenation that lasts for up to two years or more.
For those interested in a safe, effective, and gradual approach to anti-ageing, Lenisna at aesthetic clinic INNODERM in London provides expert care and excellent outcomes. Experience the transformative power of Lenisna and enjoy a refreshed, radiant appearance with minimal downtime and lasting benefits.
Last updated